Services


Lab technician

TMIC offers custom tailored metabolomics services that are many times faster, more quantitative, and far more comprehensive than any other facility in North America and provides a single source destination for fee-for-service metabolic profiling including comprehensive metabolite identification, quantification, and analysis for the medical, agricultural, food processing (including functional food and nutraceutical) as well as the environmental testing markets.

Check out our brochure for more information on metabolomics services.

Available Technical Services

TMIC offers the following technical services for the analysis of biofluids, tissues, bioproducts, bioprocesses, or crops by GC-MS, LC-MS, NMR, HPLC and combined approaches:

  • Lipidomics (phospholipids, TAGs, DAGs, MAGs, CEs, and fatty acids)
  • Phytochemical analysis
  • Nutrients (general metabolite analysis)
  • Metabolic footprinting and fingerprinting
  • Food composition analysis
  • Biofuel composition analysis
  • Tissue imaging
  • Free bioinformatics tools

TMIC has extensive experience working with many types of samples and model organisms. If your organism or sample type does not appear on these lists, please contact us to see if we can still accommodate your needs. See here for more details on our available equipment.

TMIC provides comprehensive reports including metabolite identification and concentration, experimental and quality control methods, and statistical analysis. Take a look here at what your TMIC results and report would look like.

For more information, take a look at our brochures:

TMIC-Metabolomic.Analysis.Services
TMIC-Metabolomic.Analysis.Services-Metabolites
TMIC-NMR-Metabolomic.Analysis.Kit.for.Plasma.Serum.and.CSF

Our Workflow

Tmic workflow

Services

Platform Specific Metabolomic Assays - Absolute Quantitative Assays

Service
Number of compounds
!
Price (CAD) / sample
Volume
Up to 180

Academic/Government: $65

Industry: $102

30-50 µL
50-220

Academic/Government: - Serum and CSF: $75 - Other biofluids: $125/sample

Industry: - Serum and CSF: $108 - Other biofluids: $180

30-500 µL
30-40

Academic/Government: $70

Industry: $144

100 µL
30-40

Academic/Government: $280 (1st sample) $90 (each additional sample)

Industry: $420 (1st sample) $132 (each additional sample)

100 µL
Depends very heavily on sample, number of targets and elution times of target(s)

Academic/Government: $480 (1st sample) $110 (each additional sample)

Industry: $720 (1st sample) $132 (each additional sample)

Depends very heavily on sample, number of targets an elution times of target(s).

Academic/Government: $480 (1st sample) $110 (each additional sample)

Industry: $720 (1st sample) $132 (each)

Up to 2000

Academic/Government: $400

Industry: $600

Global (Untargeted) Metabolomic Profiling - Untargeted Assays

Service
Number of compounds
!
Price (CAD) / sample
Volume
25-80

Academic/Government: $2,800 + sample preparation (assuming 100 samples and 2 classes)

Industry: $4,200 + sample preparation (assuming 100 samples and 2 classes)

>2000

Academic/Government: $200 + sample prep, $75/hour for data analysis

Industry: $420 + sample preparation assuming standard GC×GC column configuration works – i.e. no custom method development, $180/hour for data analysis

6000 - 10000

Academic/Government: $400 (1st sample) $120 for 2 UPLC-MS runs per sample $240 for 4 UPLC-MS runs per sample $75/hour for data analysis

Industry: $800 (1st sample) $240 for 2 UPLC-MS runs per sample $480 for 4 UPLC-MS runs per sample $150/hour for data analysis

75 µL
>5000 features

Academic/Government: $140 for 2 RPLC-MS runs per sample (relative quantification); $280 for 2 RPLC-MS/MS runs per study (metabolite identification) $75/hour for data analysis

Industry: $336 per sample (relative quantification) $672 per study (metabolite identification) $180/hour for data analysis

20-200 µL or 10-50 mg lyophilized powder
>4000 features

Academic/Government: $140 for 2 RPLC-MS runs per sample (relative quantification); $280 for 2 RPLC-MS/MS runs per study (lipid identification) $75/hour for data analysis

Industry: $336 per sample (relative quantification); $672 per study (metabolite identification) $180/hour for data analysis

20-200 µL or 10-50 mg lyophilized powder
3000 - 5000

Academic/Government: $400 (1st sample) $90 per ion mode per sample (i.e. $180 per sample for (+) and (-) ESI modes)

Industry: $800 (1st sample) $180 per ion mode per sample (i.e. $360 per sample for (+) and (-) ESI modes)

75 µL
Up to 2,500 putative metabolites in urine or 1,500 in blood or 1,000 in plant extracts or 1,500 in cell extracts

Academic/Government: $120 $75/hour for data analysis

Industry: $288 $180/hour for data analysis

20-100 µL or 10-50 mg lyophilized powder
Up to 10,000 putative metabolites in urine or up to 8,000 in blood. Please contact us for other types of samples

Academic/Government: $3000 (based on running 25 fractions; the price will be reduced if less fractions are analyzed at the expense of less number of putative metabolites) $75/hour for data analysis

Industry: $5880 $180/hour for data analysis

40-200 µL or 20-100 mg lyophilized powder
>2000

Academic/Government: $400 (1st sample) $120 for 2 UPLC-MS runs per sample $75/hour for data analysis

Industry: $800 (1st sample) $240 for 2 UPLC-MS runs per sample $150/hour for data analysis

50 µL
Sample dependent

Academic/Government: $120/compound $75/hour for data analysis

Industry: $240/compound $150/hour for data analysis

Targeted Metabolomic Profiling - Class Specific Assays

Service
Number of compounds
!
Price (CAD) / sample
Volume
9

Academic/Government:$75

Industry: $108

200 µL
3

Academic/Government:$75

Industry: $108

200 µL
35

Academic/Government: $400 (1st sample) $120 for each additional sample

Industry: $800 (1st sample) $240 for each additional sample

200 µL
50

Academic/Government: $400 (1st sample) $120 for each additional sample

Industry: $800 (1st sample) $240 for each additional sample

25 µL
67

Academic/Government: $400 (1st sample) $150 for each additional sample

Industry: $800 (1st sample) $300 for each additional sample

25 µL
20

Academic/Government: $65

Industry: $85

50 µL
40-80 (sample dependent)

Academic/Government: $70

Industry: $144

200 µL
Sample dependant

Academic/Government: $400 (1st sample) $120 for 2 UPLC-MS runs per sample

Industry: $800 (1st sample) $240 for 2 UPLC MS runs per sample

100 µL
14

Academic/Government: $400 (1st sample) $120 for each additional sample

Industry: $800 (1st sample) $240 for each additional sample

25 µL
12

Academic/Government: $400 (1st sample) $120 for each additional sample

Industry: $800 (1st sample) $240 for each additional sample

250 µL
8

Academic/Government: $400 (1st sample) $120 for each additional sample

Industry: $800 (1st sample) $240 for each additional sample

200 µL
46

Academic/Government: $400 (1st sample) $120 for each additional sample

Industry: $800 (1st sample) $240 for each additional sample

>2000

Academic/Government: $200 + sample prep $75/hour for data analysis

Industry: $420 + sample preparation assuming standard GC×GC column configuration works – i.e. no custom method development $180/hour for data analysis

9

Academic/Government: $55

Industry: $90

200 µL
18

Academic/Government: $55

Industry: $90

200 µL
7

Academic/Government: $55

Industry: $90

7

Academic/Government: $55

Industry: $90

200 µL
6

Academic/Government: $55

Industry: $90

200 µL
6

Academic/Government: $55

Industry: $90

200 µL
40-50

Academic/Government: $35

Industry: $54

200 µL
up to >1000 lipids and other metabolites. Please consult for more information.

Academic/Government: $600 for detection in (+) or (-) ion mode (i.e. $1200 for both (+) and (-) ion modes)

Industry: $1200 for detection in (+) or (-) ion mode (i.e. $2400 for both (+) and (-) ion modes)

7

Academic/Government:$75

Industry: $108

200 µL

Targeted Metabolomic Profiling - Pathway Specific Assays

Service
Number of compounds
!
Price (CAD) / sample
Volume
10

Academic/Government: $75

Industry: $108

200 µL
50

Academic/Government: $400 (1st sample) $180 for each additional sample

Industry: $800 (1st sample) $360 for each additional sample

400 µL
>50

Academic/Government: $400 (1st sample) $120 for each additional sample (includes 2 UPLC-MRM/MS methods)

Industry: $800 (1st sample) $240 for each additional sample (includes 2 UPLC-MRM/MS methods)

50 µL
Sample dependent – please inquire

Academic/Government: $400 (1st sample) $120 for 2 UPLC-MS runs per sample

Industry: $960 (1st sample) $288 for 2 UPLC-MS runs per sample

50 µL
33 fatty acids; 21 acyl-carnitines

Academic/Government: $400 (1st sample) $120 for each additional sample

Industry: $800 (1st sample) $240 for each additional sample

50 µL

TMIC Customized assays

TMIC specializes in developing custom, quantitative LC-MS, GC-MS and NMR based assays for specific metabolomic applications, including biomarker validation. Please inquire for more information.

Service
Number of compounds
Price (CAD) / sample
Volume
High Abundance Metabolites in Plasma/Serum
Low Abundance Metabolites in Plasma/Serum

Human Metabolome Library

Download the Human Metabolome Library List

The Human Metabolome Library is a chemical resource with the power to help confirm, validate or quantify suspected metabolites in tissues or biofluids. The Human Library contains over 1000 compounds. Compounds are shipped in quantities of ~10mg. Please inquire for list of available compounds.

TMIC's HML is available through MetaSci Inc.

For inquiries please contact info@metasci.ca.

Metabolomic Profiling Kits

Service
Number of compounds
!
Price (CAD) / sample
Volume
47 - plasma/ serum 43 - CSF

$499

Up to 2,500 putative metabolites in urine or 1,500 in blood or 1,000 in plant extracts or 1,500 in cell extracts

$7525 $7000 (software only)

Metabolomic Reagents

Service
Number of compounds
!
Price (CAD) / sample
Volume
MCID hu001: Plain human urine
> 2000

$70

MCID hu002: Dns human urine
> 2000

$70

MCID r009: 13C DnsCl
-

$210/10 mg

MCID r010: 13C DmPA
-

$280/10 mg

MCID r012: 12C DmPA
-

$70

Up to 2,500 putative metabolites in urine or 1,500 in blood, or 1,000 in plant extracts, or 1,500 in cell extracts

$210

Up to 2,500 putative metabolites in urine or 1,500 in blood, or 1,000 in plant extracts, or 1,500 in cell extracts

$525

Up to 2,500 putative metabolites in urine or 1,500 in blood, or 1,000 in plant extracts, or 1,500 in cell extracts

$1050

Up to 2,500 putative metabolites in urine or 1,500 in blood or 1,000 in plant extracts or 1,500 in cell extracts

$210

Up to 2,500 putative metabolites in urine or 1,500 in blood or 1,000 in plant extracts or 1,500 in cell extracts

$525

Up to 2,500 putative metabolites in urine or 1,500 in blood or 1,000 in plant extracts or 1,500 in cell extracts

$1050

Bioinformatics Support

Service
Number of compounds
Price (CAD) / sample
Volume

Specialized Services

Service
Number of compounds
Price (CAD) / sample
Volume

Please note:

  • All prices quoted are in Canadian Dollars (CAD).
  • Researchers from the public sector receive ‘Academic pricing’.
  • Large projects involving a combination of 3 or more services may be eligible for discounts of 10‐15%.
  • TMIC will generally analyze pilot samples free of charge. Please contact us for details.

TMIC’s pricing model is in accordance with the Genome Canada Access policy for the Genomics Innovation Network:

  • Where the users are researchers from the public sector, pricing will be based only on the variable costs of providing the service (e.g., consumables, technicians’ salaries and consultation time)
  • Where the users are researchers from the private sector, full cost‐recovery is required, and the pricing will be based on both the variable costs as described above, and other direct costs such as overhead, amortization expense related to equipment costs, etc. Institutional overhead rates also apply to private sector projects.
  • Prices are set using the above criteria as guidelines. Variations in prices may be due to the type of relationship between the user and TMIC (collaborative or fee‐for‐service), the level of interaction required (e.g., with or without post data‐generation analysis), and the magnitude of the request which may benefit from volume cost savings. TMIC is not able to provide services to any users (collaborative or fee‐for‐service) at prices below the variable cost of the service as defined above.