Purine/pyrimidine Synthesis Pathway


Description

Quantitation of purine/pyrimidine synthesis and salvage metabolites using a combined LC-MRM/MS and high-resolution LC-MS approach for absolute (with internal standards) and relative quantitation.

Quantitative

Absolute and relative

Platform Available

UPLC-MRM/MS


Price

*Academic/Government: $400 1st sample; $120 each additional sample * *Industry: $800 1st sample; $240 each additional sample

Minimum Volume

  • Tissue: 20 mg
  • Cell: 5x10^6
  • Blood/plasma/serum: TBD
  • Urine: N/A
  • Plant: TBD


NameHMDB IDSuper ClassClass
5-aminoimidazole ribonucleotide (ribotide) (AIR)
5-aminoimidazole-4-Carboxamide Riboside (AICAR)
5-Formylamino-4-imidazolecarboxamide Ribonucleotide (FAICAR)
Carbamoyl aspartate
Carbamoyl phosphate
Carboxyaminoimidazole ribonucleotide (CAIR)
Dihydrorotate
Formylglycinamide Ribotide (FGAR)
Formylglycinamidine Ribotide (FGAM)
Glycinamide ribonucleotide (GAR)
N-Succinyl-5-aminoimidazole-4-carboxamide (SAICA)
N-Succinyl-5-aminoimidazole-4-carboxamide Riboside (SAICAR)
Orotidine-5P
Phosphoribosyl amine
IMPHMDB00175Nucleosides, nucleotides, and analoguesPurine nucleotides
UMPHMDB00288Nucleosides, nucleotides, and analoguesPyrimidine nucleotides
Phosphoribosyl pyrophosphate (PRPP)Organic oxygen compoundsOrganooxygen compounds
Ribose-5POrganic oxygen compoundsOrganooxygen compounds
OrotateOrganoheterocyclic compoundsDiazines